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AUGS/IUGA Scientific Meeting 2019
NIDDK LURN Lecture: Symptoms of Lower Urinary Trac ...
NIDDK LURN Lecture: Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN): Overview and Initial Findings
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Video Transcription
Video Summary
In this video, the presenter discusses the Symptoms of Lower Urinary Tract Dysfunction Research Network (LUT NERC) and their initial findings. The network was developed and funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in order to improve the treatment of patients with lower urinary tract symptoms (LUTs). The presenter explains that patients with LUTs present with a wide variety of symptoms that may or may not have a source in the lower urinary tract, so understanding the clinically relevant subtypes of LUTs is crucial. The network developed the Comprehensive Assessment of Self-Reported Urinary Symptoms (CASIS) questionnaire to gather patient-reported outcome measures. They also conducted studies to explore the mechanisms and biomarkers associated with LUTs. The network has recruited over 1,000 patients for their observational cohort study and collected 75,000 biospecimens. They have presented their findings at professional meetings and published 20 articles in peer-reviewed journals. The network plans to validate and refine the existing symptom-based clusters, explore biomarkers and perform further phenotyping studies to improve the treatment of LUTs.
Asset Caption
Cindy L. Amundsen, MD
Keywords
Lower Urinary Tract Dysfunction Research Network
LUT NERC
lower urinary tract symptoms
Comprehensive Assessment of Self-Reported Urinary Symptoms
CASIS questionnaire
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