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A study was conducted to evaluate the efficacy of postoperative prophylactic antibiotics in reducing the rate of urinary tract infections (UTI) in women undergoing retropubic mid-urethral synthetic sling (RMUS) surgery for stress urinary incontinence (SUI). A total of 112 charts were included for analysis from February 2014 to February 2016 at a hospital in Texas. The study found that 85% of the subjects did not develop a postoperative UTI, while 15% did. The types of prophylactic antibiotics prescribed did not have a significant impact on the UTI rates. The study also identified that the use of an indwelling Foley catheter or clean intermittent catheterization (CIC) after postoperative day one was a significant risk factor for postoperative UTI. Medication-related adverse effects were only seen in the subjects who received postoperative prophylactic antibiotics. The study has some limitations such as its retrospective design, single-center design, and assumption of medication compliance. However, it is notable for its evaluation of five different antibiotics used for postoperative prophylaxis after RMUS. Overall, the study suggests that there is no significant difference in UTI rates whether or not postoperative prophylactic antibiotics are prescribed and highlights the importance of avoiding the use of indwelling Foley catheters or CIC after postoperative day one to reduce the risk of UTIs.
Keywords
study
efficacy
postoperative prophylactic antibiotics
urinary tract infections
retropubic mid-urethral synthetic sling surgery
stress urinary incontinence
UTI rates
indwelling Foley catheter
clean intermittent catheterization
medication-related adverse effects
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