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This study aimed to determine the effectiveness of posterior biologic grafts in reducing recurrence rates of posterior vaginal wall prolapse (PVWP) following reconstructive surgery. The study included 353 patients who underwent either traditional posterior colporrhaphy (PC) or PC with a biologic graft (BG) between 2001 and 2016. The failure rates were determined by a composite of subjective and objective outcomes.<br /><br />The results showed that biologic grafts did not decrease posterior vaginal compartment recurrence rates compared to traditional PC. The failure rates were similar for both PC and BG groups when considering composite failures, subjective failures, and objective failures.<br /><br />The study also revealed some factors associated with the BG group. Patients in the BG group were more likely to be older, postmenopausal, have had a prior hysterectomy, and have undergone an apical suspension. They also had lower estimated blood loss and were less likely to undergo concurrent hysterectomy. However, the mean length of follow-up was similar for both groups.<br /><br />Among the 8 patients who returned to the operating room, only 2 had reoperations for prolapse, and one of them was in the PC group for posterior recurrence.<br /><br />In conclusion, the use of biologic grafts did not result in lower recurrence rates of PVWP compared to traditional PC. This study adds to the existing literature that has shown varying results regarding the effectiveness of posterior biologic grafts in pelvic organ prolapse repair.<br /><br />References:<br />- Grimes CL, et al. Long-term outcomes after native tissue vs. biological graft-augmented repair in the posterior compartment.<br />- Paraiso MF, et al. Rectocele repair: a randomized trial of three surgical techniques including graft augmentation.<br />- Schimpf MO, et al. Graft and Mesh Use in Transvaginal Prolapse Repair: A Systematic Review.<br />- Sung VW, et al. Porcine subintestinal submucosal graft augmentation for rectocele repair: a randomized controlled trial.
Keywords
posterior biologic grafts
recurrence rates
posterior vaginal wall prolapse
reconstructive surgery
traditional posterior colporrhaphy
failure rates
postmenopausal
prior hysterectomy
apical suspension
prolapse repair
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