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The study focused on the barriers that socially disadvantaged women face when enrolling in clinical trials. The researchers conducted cognitive interviews with 19 women who had pelvic organ prolapse to understand their perspectives. They used in vivo coding, interpretive coding, and behavioral coding to summarize the ideas discussed and evaluate understanding of the questions. The results showed that underrepresented women were aware of the barriers they faced in enrolling in clinical trials. The main barriers identified were the fear of being assigned to a specific treatment group, lack of understanding about blinding treatment group assignment, and the financial burden of participating in a trial. On the other hand, positive influences for enrollment in clinical trials included wanting to help their doctor, identifying with the research problem, and altruism. The study also cited previous research that highlighted disparities in participation in clinical trials based on race, sex, and age. Overall, the findings suggest that socially disadvantaged women face specific obstacles when it comes to enrolling in surgical trials and that understanding these barriers can help address the lack of diversity in clinical trials.
Keywords
barriers
socially disadvantaged women
clinical trials
cognitive interviews
underrepresented women
fear of treatment group assignment
financial burden
positive influences
disparities
surgical trials
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