E-Posters-10030_Kadam

10030_Kadam_Halani

Pdf Summary

A meta-analysis of neuroimaging studies was conducted to identify the regions of the brain that are activated during bladder filling and rectal distention in healthy adults. The study included 17 studies on rectal distention with a total of 284 subjects, and 14 studies on bladder filling with a total of 197 subjects. The analysis revealed that rectal distention activates the right insula, left insula, bilateral thalamus, and right and left postcentral gyri. Bladder filling activates the right insula, bilateral thalamus, and right brainstem. The analysis also showed that both bladder filling and rectal distention activate the right insula. This common activation of the insula, which is responsible for interoception or the sense of the body's physiological state, may explain the coexistence of bladder and defecatory symptoms in pelvic floor disorders. The study suggests that there is overlapping brain activation during bladder filling and rectal distention in healthy adults. This information may contribute to a better understanding of the relationship between urinary voiding and defecatory dysfunction in individuals with pelvic floor disorders.

Keywords

neuroimaging

bladder filling

rectal distention

healthy adults

insula activation

thalamus activation

postcentral gyri activation

brainstem activation

interoception

pelvic floor disorders