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This clinical study aimed to measure the impact of pelvic mesh implant surgery (PMIS) on the development of pelvic pain in women undergoing surgery for pelvic organ prolapse (POP) and/or urinary incontinence (UI). The study also aimed to identify clinical factors associated with pain development. The study included a cohort of women classified as either undergoing repair with PMIS or native tissue repair (NTR). Pain was assessed using a quantitative sensory testing (QST) protocol, and other measures included pain perception, mood, and baseline physical, mental, and sexual health. The primary outcome was the difference in postoperative pelvic pain score between PMIS and NTR. <br /><br />Key findings from the study showed that women with PMIS had mildly increased postoperative pelvic pain compared to those with NTR. These women also experienced more somatic and neuropathic pain at both pelvic and non-pelvic sites, suggesting that the presence of mesh implants may contribute to peripheral and centrally-mediated pain. <br /><br />The pain exam scores at 6 weeks postoperative showed significant differences between PMIS and NTR, with higher pain scores in the PMIS group. The pain questionnaire scores also revealed differences in pain perception, with the PMIS group reporting higher scores on the McGill questionnaire's tender subscale and aching pain subscale.<br /><br />In conclusion, this study suggests that PMIS may contribute to the development of pelvic pain in women undergoing surgery for POP and/or UI. The presence of mesh implants was associated with increased somatic and neuropathic pain at both pelvic and non-pelvic sites. These findings highlight the importance of understanding the clinical correlates of pelvic pain following PMIS and may inform future research and treatment options for women experiencing this pain.
Keywords
pelvic mesh implant surgery
pelvic pain
women
surgery
pelvic organ prolapse
urinary incontinence
clinical factors
quantitative sensory testing
pain perception
postoperative pelvic pain
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