E-Posters-10035

10035_Brady

Pdf Summary

The Bladder Environment: Microbiota and Oxygen Relationships (BE MOR) study aimed to understand the relationship between female urinary microbiota (FUM) and bladder urine oxygen tension (BUOT). The study included female urogynecology patients who were willing to undergo transurethral catheterization. BUOT values were determined using a non-invasive flow-through oxygen sensor system. <br /><br />The study found that there was an association between BUOT and FUM, with lower BUOT values being linked to an increased representation of known uropathogens. The study included a total of 70 participants, with 65% of them having measurable BUOT values. Most participants were Caucasian (81.4%) and post-menopausal (78.6%), with a mean age of 65 years. The mean BUOT value was 24.84 mmHg.<br /><br />The participants were divided into three groups based on their BUOT values: low, middle, and high. The study found no significant differences in age, BMI, ethnicity, menopausal status, or smoking status between the three groups. However, there was a trend for less microbial diversity in the low BUOT group compared to the other two groups. Escherichia and Staphylococcus were the dominant bacteria in the low BUOT group.<br /><br />The study highlights the relationship between BUOT and FUM and the influence of oxygen on microbial communities in the female urinary system. Further research is needed to better understand these relationships and their implications for urogynecology patients.

Keywords

Bladder Environment

Microbiota

Oxygen Relationships

Female Urinary Microbiota

Bladder Urine Oxygen Tension

Urogynecology Patients

Transurethral Catheterization

Uropathogens

Caucasian

Post-Menopausal