E-Posters-10051

10051_Jarnagin
Pdf Summary
This document presents a study on the use of a regenerative amniotic tissue product (ATP) for the treatment of chronic pelvic pain (CPP) with a pudendal neuralgia component. The study involved the injection of ATP into the pudendal nerve area in 64 patients with CPP. After a follow-up period of 6 weeks, the results showed that 67% of the patients reported complete or near complete resolution of their CPP pain, with an additional 23% experiencing moderate pain relief. Only 9% of patients reported no relief.<br /><br />The study also discusses the mechanism of action of the ATP, suggesting that tissue restoration and the immunomodulatory and regenerative components present in the product play a significant role in its therapeutic action. The presence of live regenerative cells is not necessary for the therapeutic effect. The study speculates that microRNAs present in the product may also contribute to its therapeutic action.<br /><br />Compared to other regenerative therapies, the use of ATP has several advantages. It does not involve the use of fetal stem cells or induced pluripotent stem cells, avoiding teratogenic effects. It does not require tissue harvesting from the patient, eliminating ethical concerns. Additionally, the ATP has no serious side effects and is compliant with FDA regulations on human cell and tissue products. It is also covered by many insurance plans, including Medicare.<br /><br />The document also provides background information on CPP and its association with pudendal neuralgia. CPP is a common and debilitating condition among women, affecting their quality of life. It is often difficult to treat due to its multiple etiologies. Previous studies have suggested that stem cells may be beneficial for treating chronic pain associated with CPP.<br /><br />The study concludes that treatment with the ATP resulted in significant pain relief in over 90% of patients with CPP and pudendal neuralgia. The use of ATP offers a novel and effective therapeutic approach for patients suffering from this condition.
Keywords
regenerative amniotic tissue product
chronic pelvic pain
pudendal neuralgia
pain relief
tissue restoration
immunomodulatory
regenerative components
microRNAs
stem cells
therapeutic approach