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The study investigated the impact of age on perioperative adverse events (AE) after obliterative vaginal surgery with colpocleisis. The retrospective cohort study included 371 women who underwent colpocleisis between 2010 and 2013. Perioperative AEs were defined as any deviation from a normal postoperative course within 12 weeks of surgery.<br /><br />Results showed that 6.2% of the women experienced a serious AE, which included death, life-threatening event, hospitalization, or persistent/permanent disability. Age was not initially predictive of serious AEs on univariable analysis. However, further analysis revealed that age 78 was the best cut-point for predicting perioperative AEs.<br /><br />Additional findings showed that 25.3% of the women experienced at least one adverse event, with urinary tract infections (UTIs) being the most common complication. Furthermore, 4.9% of the women had a hospital readmission within 30 days.<br /><br />Univariable logistic regression analysis identified age, history of recurrent UTIs, and history of urinary retention as significant predictors of perioperative AEs. However, only age and history of urinary retention remained significant in the final multivariable model.<br /><br />The study concluded that age and history of urinary retention are predictors of perioperative adverse events, with age 78 being the best cut-point for predicting these events. For each additional year of age, subjects are 1.05 times as likely to experience an adverse event. It is important to consider these factors when assessing the risk of perioperative complications in obliterative vaginal surgery with colpocleisis.
Keywords
age
perioperative adverse events
obliterative vaginal surgery
colpocleisis
retrospective cohort study
women
postoperative course
serious adverse events
urinary tract infections
hospital readmission
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