E-Posters-10130

10130_Henley
Pdf Summary
This pilot study aimed to investigate the association between vitamin D deficiency and female overactive bladder syndrome (OAB) in a population of women receiving treatment at an academic medical center in the Southeast. The study included a total of 65 women, with 35 controls and 29 cases. After analysis, it was found that 23% of the subjects were missing vitamin D levels, leaving only 25 controls and 25 cases that could be analyzed.<br /><br />The characteristics of the sample population showed that the mean vitamin D level was 23.6 ng/mL, the mean age was 48 years, and the mean BMI was 32.0 kg/m2. In terms of incontinence subtypes, the prevalence of any incontinence was 59%, pure urge (OAB) was 34%, pure stress was 13%, mixed was 11%, and none was 40%.<br /><br />The study found that those with vitamin D deficiency had approximately twice the odds of having OAB than those with normal vitamin D levels. The prevalence of vitamin D deficiency by ethnicity was 59% overall, 33% for white, 1% for black, and 1% for Asian. The prevalence of OAB by ethnicity was 66% overall, 36% for pure urge (OAB), 16% for pure stress, and 14% for mixed.<br /><br />The data indicated a positive association between low vitamin D levels and prevalence of OAB, although the lack of statistical significance was likely due to the small sample size. The study suggests that a larger study may yield significant results.<br /><br />The authors recommend pursuing a more highly powered case-control study and a randomized controlled trial to further investigate the association between vitamin D deficiency and OAB. Currently, there are no guidelines for vitamin D screening in the OAB population, and quality evidence is needed before guidelines can be established.
Keywords
pilot study
vitamin D deficiency
female overactive bladder syndrome
OAB
association
prevalence
ethnicity
statistical significance
small sample size
guidelines