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This study aimed to determine the prevalence of stress urinary incontinence (SUI) and intrinsic sphincter deficiency (ISD) in women with different stages of pelvic organ prolapse (POP) and to examine if the location of the highest severity stage of POP is associated with ISD prevalence. A total of 258 patients met the inclusion criteria and underwent pelvic examination and prolapse staging using the POP-Q staging system. Patients with stage I, II, III, or IV prolapse were included in the study.<br /><br />The results showed that ISD was not limited to a specific prolapse compartment and was most prevalent in stage IV POP, followed by stage I. The study also found that the location of the highest severity stage of POP was not associated with ISD prevalence. This information can assist practitioners in preoperative planning and counseling for women with POP who may also have ISD.<br /><br />The study included patients who had symptomatic stress incontinence as well as those who were asymptomatic but had occult stress incontinence. Complex multichannel urodynamic testing was performed on all patients to diagnose ISD. ISD was defined as having abdominal leak point pressure (ALPP) ≤60cm H2O and/or maximum urethral closure pressure (MUCP) ≤20cm H2O.<br /><br />Overall, 16.3% of the patients were diagnosed with ISD. Of those diagnosed with ISD, 27% had stage IV POP, 21% had stage I, 19% had stage III, and 7.4% had stage II. The prevalence of ISD was significantly different across the four stages of POP. However, the study did not find a significant association between the location of the highest severity stage of POP and ISD prevalence.<br /><br />Further research is needed to confirm these findings through larger prospective studies. Understanding the prevalence and distribution of ISD in women with different stages of POP can help guide treatment decisions and improve patient outcomes.
Keywords
stress urinary incontinence
intrinsic sphincter deficiency
prevalence
women
pelvic organ prolapse
POP-Q staging system
prolapse compartment
preoperative planning
multichannel urodynamic testing
abdominal leak point pressure
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