E-Posters-10143

10143_Yordan

Pdf Summary

This document discusses the use of porcine urinary matrix for repairs of pelvic organ prolapse (POP). POP can cause sexual, defecatory, and urinary dysfunction and is a common reason for hysterectomy. Native tissue augmentation, using synthetic mesh or biologic-derived graft, can improve the durability of repair but can also lead to complications. This study conducted a retrospective review of charts between 2010-2015 and found that using porcine urinary matrix resulted in support and durability of repair. Preoperative POP-Q for level 1 and level 2 support ranged from -2 to +6 at presenting part. There were a total of 93 pelvic reconstruction procedures, including anterior repairs, vaginal paravaginal repairs, and sacrospinous colpopexies. Postoperative POP-Q scores at 3-72 months showed durable global level 1 and 2 support. There were no significant surgical or product complications identified, with only 2 anatomical failures and 1 symptomatic case needing reoperation. The use of porcine urinary matrix was found to be technically easy and provided durable POP repair without complications or host-graft rejection. However, this study has limitations as it is an observational case series with no controls or randomization. Future directions for research include a prospective trial comparing different types of repairs and evaluating quality of life and cost effectiveness.

Keywords

porcine urinary matrix

pelvic organ prolapse

durable repair

retrospective review

POP-Q scores

anatomical failures

reoperation

complications

observational case series

prospective trial