E-Posters-10143

Pdf Summary

This document discusses the use of porcine urinary matrix for repairs of pelvic organ prolapse (POP). POP can cause sexual, defecatory, and urinary dysfunction and is a common reason for hysterectomy. Native tissue augmentation, using synthetic mesh or biologic-derived graft, can improve the durability of repair but can also lead to complications. This study conducted a retrospective review of charts between 2010-2015 and found that using porcine urinary matrix resulted in support and durability of repair. Preoperative POP-Q for level 1 and level 2 support ranged from -2 to +6 at presenting part. There were a total of 93 pelvic reconstruction procedures, including anterior repairs, vaginal paravaginal repairs, and sacrospinous colpopexies. Postoperative POP-Q scores at 3-72 months showed durable global level 1 and 2 support. There were no significant surgical or product complications identified, with only 2 anatomical failures and 1 symptomatic case needing reoperation. The use of porcine urinary matrix was found to be technically easy and provided durable POP repair without complications or host-graft rejection. However, this study has limitations as it is an observational case series with no controls or randomization. Future directions for research include a prospective trial comparing different types of repairs and evaluating quality of life and cost effectiveness.

Meta Tag

Concept Pelvic Organ Prolapse

Concept Tissue Augmentation

Concept Synthetic Mesh

Concept Biologic Xenograft

Concept Porcine Urinary Bladder Extracellular Matrix

Keywords

porcine urinary matrix

pelvic organ prolapse

durable repair

retrospective review

POP-Q scores

anatomical failures

reoperation

complications

observational case series

prospective trial

Pelvic Organ Prolapse

Tissue Augmentation

Synthetic Mesh

Biologic Xenograft

Porcine Urinary Bladder Extracellular Matrix