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The study aimed to characterize the prevalence of lower urinary tract symptoms (LUTS) in a population with chronic pain and identify factors associated with LUTS in this population. They found that 36-47% of the population had a positive pain questionnaire, indicating the presence of chronic pain. Among the patients analyzed, 49% had mild symptoms, 31% had moderate symptoms, and 20% had severe symptoms on the American Urological Association Symptom Index (AUA-SI), which assesses urinary symptoms. Logistic regression models showed that central sensitization, pain, urgency, and frequency were significantly associated with moderate to severe urinary symptoms on the AUA-SI. However, vestibulodynia was associated with lower odds of having moderate to severe urinary symptoms.<br /><br />The study excluded patients with a diagnosis of interstitial cystitis or bladder pain syndrome. The patients completed various pain questionnaires, including the Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS), Pelvic Pain and Urgency/Frequency Symptoms Scale (PUF), and Central Sensitization Inventory (CSI). The demographics of the 144 patients analyzed included a median age of 43.0 and a median BMI of 25.3. The most common diagnoses were dyspareunia, myofascial pain, and vulvar/vestibular pain.<br /><br />In conclusion, the study found a high prevalence of LUTS among patients with chronic pain. Central sensitization, as demonstrated by the CSI, and pain, urgency, and frequency, as demonstrated by the PUF, were significantly associated with moderate to severe urinary symptoms on the AUA-SI. Vestibulodynia was associated with lower odds of having moderate to severe urinary symptoms. Further research is needed to understand the relationship between pelvic pain and bladder symptoms and to identify effective treatment strategies for this population.
Keywords
prevalence
lower urinary tract symptoms
LUTS
chronic pain
pain questionnaire
AUA-SI
central sensitization
urgency
frequency
vestibulodynia
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