E-Posters-10171

10171_Martin

Pdf Summary

This study retrospectively reviews the use of baclofen in reducing post-void residuals in patients with dysfunctional or obstructive voiding. The objective of the study was to determine the efficacy of baclofen in improving bladder emptying in these patients. <br /><br />A total of 57 patients were included in the study, all of whom had a diagnosis of dysfunctional voiding or incomplete voiding. Patients were started on baclofen at a dose of 10 mg twice a day, with titration based on efficacy and side effects. <br /><br />The primary outcome measured was a significant decrease in post-void residual volume. The average pre-treatment PVR was 130 ml, and after treatment with baclofen, there was an average decrease of 60 ml. 62% of patients with a PVR >100 ml had a PVR of <100 ml after treatment. <br /><br />When stratified by patients with obstructed voiding due to a sub-urethral sling versus patients with dysfunctional voiding, both groups showed a significant decrease in PVR. The subjective score of urinary symptoms also showed improvement, with 49% of patients reporting somewhat improved urinary stream and 11% reporting greatly improved urinary stream after taking baclofen. <br /><br />In conclusion, this study suggests that baclofen is effective in reducing post-void residual volume in patients with dysfunctional or obstructive voiding. Further prospective studies are needed to evaluate the efficacy of baclofen in these patients. <br /><br />Overall, this study highlights the potential of baclofen as a treatment option for urogynecologic patients with voiding dysfunction, particularly those with dysfunctional or obstructed voiding.

Keywords

baclofen

post-void residuals

dysfunctional voiding

obstructive voiding

bladder emptying

efficacy

titration

urinary symptoms

urogynecologic patients

voiding dysfunction