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This study retrospectively reviews the use of baclofen in reducing post-void residuals in patients with dysfunctional or obstructive voiding. The objective of the study was to determine the efficacy of baclofen in improving bladder emptying in these patients. <br /><br />A total of 57 patients were included in the study, all of whom had a diagnosis of dysfunctional voiding or incomplete voiding. Patients were started on baclofen at a dose of 10 mg twice a day, with titration based on efficacy and side effects. <br /><br />The primary outcome measured was a significant decrease in post-void residual volume. The average pre-treatment PVR was 130 ml, and after treatment with baclofen, there was an average decrease of 60 ml. 62% of patients with a PVR >100 ml had a PVR of <100 ml after treatment. <br /><br />When stratified by patients with obstructed voiding due to a sub-urethral sling versus patients with dysfunctional voiding, both groups showed a significant decrease in PVR. The subjective score of urinary symptoms also showed improvement, with 49% of patients reporting somewhat improved urinary stream and 11% reporting greatly improved urinary stream after taking baclofen. <br /><br />In conclusion, this study suggests that baclofen is effective in reducing post-void residual volume in patients with dysfunctional or obstructive voiding. Further prospective studies are needed to evaluate the efficacy of baclofen in these patients. <br /><br />Overall, this study highlights the potential of baclofen as a treatment option for urogynecologic patients with voiding dysfunction, particularly those with dysfunctional or obstructed voiding.
Meta Tag
Concept
Baclofen
Concept
Dysfunctional Voiding
Concept
Obstructive Voiding
Concept
Urinary Retention
Concept
Urethral sphincter
Keywords
baclofen
post-void residuals
dysfunctional voiding
obstructive voiding
bladder emptying
efficacy
titration
urinary symptoms
urogynecologic patients
voiding dysfunction
Baclofen
Dysfunctional Voiding
Obstructive Voiding
Urinary Retention
Urethral sphincter
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