E-Posters-10224

10224_Askew

Pdf Summary

A retrospective cohort study conducted at Duke University Health System sought to determine whether the weight of mesh used in robotic sacrocolpopexy (RSC) affected the time to failure in patients undergoing the procedure. The study included 466 women who underwent RSC for prolapse between February 2012 and September 2016. The primary outcome was time to anatomic failure, defined as recurrent prolapse beyond the hymen or retreatment with surgery or a pessary. Secondary outcomes included compartment of failure and mesh exposure.<br /><br />The study found that the use of ultralight mesh (mesh weight < 20 g/m^2) was associated with a higher risk of failure compared to heavier weight mesh (mesh weight > 35 g/m^2). Kaplan Meier curves showed significantly different survival distributions between the two groups. Cox proportional hazards analysis revealed that the hazard of failure within three years was twice as high with ultralight mesh and five times as high in the anterior compartment. Mesh exposure was significantly less common in the ultralight mesh group. The median follow-up time was significantly shorter in the ultralight group.<br /><br />The study suggests that the weight of mesh used in RSC may affect the integrity and durability of repairs for prolapse. While ultralight mesh has certain benefits, such as decreased mesh exposure and mechanical properties similar to native tissue, it may be associated with an increased risk of failure. The findings highlight the need to consider mesh weight when balancing the risk of failure, recurrence, and mesh exposure in prolapse repairs.<br /><br />It is important to note that this study was retrospective and limited to a single institution, which may affect the generalizability of the results. Further research is needed to validate these findings and explore the optimal mesh weight for RSC in prolapse repairs.

Keywords

retrospective cohort study

weight of mesh

robotic sacrocolpopexy

time to failure

ultralight mesh

heavier weight mesh

anatomic failure

mesh exposure

hazard of failure

prolapse repairs