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A study conducted by researchers from the University of North Carolina at Chapel Hill examined the utility of preoperative laboratory testing in urogynecologic surgery, particularly for older women. The study aimed to compare the prevalence of abnormal preoperative labs among older (≥ 65 years) and younger (50-64 years) women and to determine the changes in perioperative management that occurred in response to abnormal labs.<br /><br />The study included a retrospective cohort of women aged 50 years and above who underwent surgery for pelvic organ prolapse and/or stress urinary incontinence between September 2015 and October 2016. Women undergoing specific surgeries were excluded from the study. Abnormal lab values were defined based on clinically relevant institutional reference ranges.<br /><br />The key findings of the study showed that older women had a higher rate of abnormal preoperative labs, suggesting that age may be a criterion for lab testing, particularly for complete blood counts (CBC) and basic metabolic panels (BMP). Additionally, a significant proportion of women (37.5%) experienced changes in perioperative management in response to abnormal lab results, with 25% requiring more than one intervention.<br /><br />The primary outcome of the study revealed that 18.3% of women had at least one abnormal lab result. Older women had a higher risk of having at least one abnormal lab result compared to their younger counterparts (28.7% vs 10.7%). The multivariable logistic regression model, adjusting for race, hypertension, diabetes mellitus, and smoking, found that older age and smoking were associated with an increased risk of abnormal lab results.<br /><br />In conclusion, the study suggests that older women undergoing urogynecologic surgery have a higher risk of abnormal preoperative labs, supporting the use of age as a criterion for lab testing. The study also highlights the need for changes in perioperative management in response to abnormal lab results in order to optimize patient care and outcomes.
Keywords
preoperative laboratory testing
urogynecologic surgery
older women
younger women
abnormal preoperative labs
perioperative management
pelvic organ prolapse
stress urinary incontinence
complete blood counts
basic metabolic panels
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