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10236_Dmochowski
10236_Dmochowski
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This study examines the use of radiofrequency (RF) energy to selectively target and ablate the nerve rich layers beneath the trigone in patients with urgency urinary incontinence (UUI) associated with overactive bladder (OAB). The objective of the study is to compare the efficacy of two different ablation modalities in treating these patients. <br /><br />The results show that both groups experienced significant improvement in OAB symptoms at 12 weeks post-procedure. Group B, which received deeper, contiguous ablations, showed a greater magnitude of response in urgency episodes, total urgency and frequency score (TUFS), and UUI. LUTS was reported in 36.7% of subjects, with 10.2% reporting a urinary tract infection (UTI) and one case of subjective retention.<br /><br />The recommended treatment parameters include proper patient selection, contiguous ablations across the trigone, and effacement of nerves into the paravaginal space. <br /><br />Baseline demographic data indicates that the mean age of the subjects is 67.3 years, with a mean OAB duration of 11.5 years. The mean number of voids per day is 12.3, urgency episodes per day is 8.8, TUFS is 36.6, and UUI per day is 4.3.<br /><br />No adverse events were reported during the procedure, and there were no instances of self-catheterization following the procedure.<br /><br />Overall, selective RF ablation of the trigone shows promise as a treatment for OAB patients with urgency urinary incontinence. The Group B therapy approach appears to provide the greatest magnitude of response while maintaining patient safety. Further studies are needed to confirm these results.
Keywords
radiofrequency energy
nerve ablation
trigone
urgency urinary incontinence
overactive bladder
ablation modalities
OAB symptoms
LUTS
urinary tract infection
subjective retention
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