E-Posters-10242

10242_Kohli

Pdf Summary

This study aimed to compare the bladder trauma associated with two different urinary catheters in a sheep model. The traditional round balloon Foley catheter was compared to a new catheter design called CystoSure with a low profile flat pancake balloon, minimal tip length, and open-ended distal suction ports. Six ewes were randomly assigned to one of the two catheters and after 96 hours of bladder drainage, their bladders were harvested for analysis.<br /><br />The results showed marked differences in the degree of mucosal injury between the two catheters. The Foley catheters had a mean injured surface area of 7.2% compared to only 1.8% in the CystoSure catheters. The Foley catheters also had a higher mean edematous area of 26.9% compared to 13% in CystoSure catheters. These findings suggest that the design of the CystoSure catheter, with its rounded tip and reduced balloon base to tip profile, resulted in significantly reduced mucosal damage to the bladder.<br /><br />This reduced bladder trauma may have important clinical implications. A damaged bladder surface can predispose to infection, while an intact mucosal surface may serve as a barrier to infection. Therefore, modifying the design of urinary catheters to reduce bladder trauma could potentially reduce the incidence of catheter-associated urinary tract infections (CAUTI).<br /><br />While these initial animal results are encouraging, further studies and clinical trials are needed to validate these findings in human subjects. However, this study highlights the potential of better catheter design to minimize bladder trauma and improve patient outcomes.

Keywords

bladder trauma

urinary catheters

sheep model

Foley catheter

CystoSure

mucosal injury

edematous area

bladder damage

catheter-associated urinary tract infections

patient outcomes