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A study was conducted to investigate the effects of common vaginal products on the growth of E. coli and Lactobacillus, as well as their potential implications for urinary tract infection (UTI) risk in postmenopausal women. Vaginal lubricants, moisturizers, and pH balancers are commonly used by patients, but little is known about their effects on the vaginal microbiota. <br /><br />The study found that most vaginal products significantly inhibited the growth of E. coli. This effect was observed with both laboratory and clinical strains of E. coli. Trimo-San and Replens moisturizer were found to inhibit the growth of both L. crispatus and L. iners, while KY Jelly and Replens lubricant only inhibited the growth of E. coli, not Lactobacillus. <br /><br />It is important to note that the study does not provide information on the effect of these products on vaginal epithelial cells or their applicability to clinical conditions. Additionally, in vivo models for studying the vaginal microbiota are lacking. However, maintaining urogenital health and preventing altered flora are important for decreasing a woman's risk for UTIs. Therefore, preventive treatments for recurrent UTIs should consider the impact of vaginal products on the vaginal microbiota. <br /><br />In conclusion, common vaginal products have been shown to inhibit the growth of both E. coli and Lactobacillus. Trimo-San and Replens moisturizer inhibit the growth of both strains, while KY Jelly and Replens lubricant only inhibit the growth of E. coli. Further research is needed to better understand the impact of these products on vaginal health and their implications for UTI risk.
Keywords
vaginal products
E. coli growth
Lactobacillus growth
urinary tract infection
postmenopausal women
vaginal microbiota
vaginal lubricants
moisturizers
pH balancers
vaginal health
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