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Compartment of Pelvic Organ Prolapse Repair and Ri ...
Compartment of Pelvic Organ Prolapse Repair and Risk of Post Operative Urinary Tract Infection: A Retrospective Cohort Study of Patients in the National Surgical Quality Improvement Program Database - Fady Shehata, MBBCH/MSC, FRCS(C)
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This retrospective cohort study aimed to investigate the association between the compartment of pelvic organ prolapse (POP) repair surgery and the risk of post-operative urinary tract infection (UTI). The study included patients who underwent procedures for POP repair between 2014 and 2017, identified from the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) database.<br /><br />The primary outcome of interest was the diagnosis of UTI within 30 days following surgery. Logistic regression analysis was used to assess the association, adjusting for various factors including diabetes, hypertension, inpatient admission, body mass index, functional status, age, and American Society of Anesthesiologists class.<br /><br />The results showed that anterior compartment prolapse repair was associated with an increased risk of post-operative UTI. Additionally, advanced patient age (>80 years old) and inpatient status were also found to be statistically significant independent risk factors for post-operative UTI among patients undergoing prolapse repair surgery.<br /><br />The study concluded that patients undergoing anterior compartment prolapse repair may benefit from additional interventions to reduce the risk of post-operative UTI. The findings also highlight the importance of considering patient age and surgical setting (inpatient vs outpatient) when evaluating the risk of UTI in patients undergoing prolapse repair surgery.<br /><br />It should be noted that several authors involved in the study disclosed financial interests or relationships with pharmaceutical companies. The study was conducted by the Division of Urogynecology and Pelvic Reconstructive Surgery in the Department of Obstetrics and Gynecology, and the Division of Urology in the Department of Surgery, both at the University of Ottawa in Canada. Correspondence can be directed to Fady Shehata via email or at the Women's Health Center in Ottawa, Canada.
Keywords
retrospective cohort study
pelvic organ prolapse
POP repair surgery
post-operative urinary tract infection
logistic regression analysis
anterior compartment prolapse repair
patient age
inpatient status
prolapse repair surgery
surgical setting
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