E-Posters-Does Menopausal Status Affect Uropathogen and Antimicrobial Resistance Patterns in Women?

Does Menopausal Status Affect Uropathogen and Antimicrobial Resistance Patterns in Women? - Kristen Venuti, MD

Pdf Summary

The study aimed to compare the prevalence of uropathogens and antibiotic resistance patterns between pre- and post-menopausal women with community-acquired urinary tract infections (UTIs). The study included 370 women with a mean age of 66.7 years. Most participants were Caucasian (94.1%) and post-menopausal (88.6%). The study found that there was no significant difference between pre- and post-menopausal women in terms of the proportion of E.coli UTIs. However, there was a difference in the proportion of "other" bacterial isolates, with pre-menopausal women having a higher proportion of rare uropathogens. Most antimicrobial susceptibility patterns were similar between the two groups, and there was no difference in the proportion of pansensitive UTIs. <br /><br />The study concluded that menopausal status did not significantly impact the prevalence of specific uropathogens or increase antibiotic resistance, except for the presence of rarer uropathogens in pre-menopausal women. A history of recurrent UTI did increase the odds of resistant, non-E.coli UTIs. Additionally, women without a history of recurrent UTI had an increased odds of having a pan-sensitive urine culture. <br /><br />The study also mentioned that urinary tract infections are common among women of all age groups, and the prevalence increases with age. Investigating patterns of antimicrobial resistance and susceptibility is important for directing appropriate antibiotic therapy. <br /><br />Overall, the study found that menopausal status did not have a significant effect on uropathogens and antibiotic resistance patterns in women with community-acquired UTIs, except for the presence of rarer uropathogens in pre-menopausal women.

Keywords

uropathogens

antibiotic resistance

prevalence

community-acquired

urinary tract infections

menopausal women

E.coli UTIs

rare uropathogens

antimicrobial susceptibility patterns

pansensitive UTIs