E-Posters-Impact of Preoperative Vaginal Estrogen Use on Perceived Surgical Complexity of Vaginal Prolapse Repair

Impact of Preoperative Vaginal Estrogen Use on Perceived Surgical Complexity of Vaginal Prolapse Repair - Anna L Romanova, MD

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This study aimed to determine the impact of preoperative vaginal estrogen (VE) use on the perceived surgical complexity of vaginal prolapse repair. It was hypothesized that VE use would be associated with a lesser degree of surgical complexity as perceived by the surgeon. <br /><br />The study conducted a secondary analysis of a prospective cohort of women aged 60 years and older undergoing vaginal prolapse repair. The primary outcome was case complexity, determined by each surgeon immediately upon surgery completion as "Easier than average", "Average", or "More difficult than average". Secondary outcomes included procedure length, estimated blood loss, intraoperative complications, postoperative vaginal packing, failed voiding trial, and 2-week postoperative pain score. The analysis was conducted using chi-square/Fisher's exact and Student's T tests/Mann Whitney U.<br /><br />Of the 129 women enrolled, 85 were included in the analysis. The mean age was 74 years, and most women had Stage III pelvic organ prolapse. Approximately 30% of the women used preoperative VE, with the majority having used it for more than one year.<br /><br />The study found that preoperative VE use was not significantly associated with the perceived surgical complexity of vaginal prolapse repair. Additionally, VE use was not associated with other demographic factors or perioperative outcomes. There was no statistically significant difference in the secondary outcomes by vaginal estrogen use.<br /><br />The authors concluded that further research is needed to guide recommendations for the use of VE prior to vaginal surgery for pelvic organ prolapse. Overall, this study suggests that preoperative VE use does not have a significant impact on the perceived surgical complexity of vaginal prolapse repair.

Keywords

preoperative vaginal estrogen use

surgical complexity

vaginal prolapse repair

surgeon perception

secondary analysis

prospective cohort

case complexity

procedure length

estimated blood loss

intraoperative complications