E-Posters-Initial Experience of a 4-Arm, Ultra-Lightweight Type 1 Polypropylene Transvaginal Mesh (Restorelle® Direct Fix Anterior Mesh) in Treatment of Pelvic Organ Prolapse

Initial Experience of a 4-Arm, Ultra-Lightweight Type 1 Polypropylene Transvaginal Mesh (Restorelle® Direct Fix Anterior Mesh) in Treatment of Pelvic Organ Prolapse - Jill C S Lee, MBChB, MSc, MRCP, MRCOG

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This study reports the initial experience of a single urogynecological center in Singapore with the use of a 4-arm, ultra-lightweight polypropylene mesh called Restorelle® DirectFix Anterior for the treatment of pelvic organ prolapse (POP). The purpose of the study was to analyze surgical, anatomical, and symptom-related outcomes of patients treated with this mesh. <br /><br />A total of 80 patients were enrolled in the study between July 2017 and September 2018. The demographics of the patients were described in Table 1, which showed that the mean age was 66.8 years and the mean BMI was 25.1 kg/m2. All patients in this cohort underwent concomitant gynecological surgery. The surgical and peri-operative outcomes of these patients were summarized in Table 4.<br /><br />Follow-up data was collected until 1-year post-treatment. Out of the 80 patients, 98.8% and 90% returned for follow-up at 1 and 6 months, respectively. Only 63 patients were followed up for over 1 year, of whom 69.8% returned for follow-up.<br /><br />The post-surgical outcomes, including subjective and objective cure rates, were provided in Table 5. The subjective cure rate was defined as patients who had no complaints or symptoms of a lump, while the objective cure rate was defined as patients who did not have Grade 2-4 recurrent cystourethrocele. The satisfaction rate among patients was high, with 98.7% at 1 month, 100% at 6 months, and 100% at 1 year.<br /><br />The study concluded that Restorelle® DirectFix Anterior mesh provided high anatomical and symptomatic cure rates for Grades 3 and 4 and recurrent cystourethroceles with good patient satisfaction. These findings can benefit pre-operative counseling for patients in centers where transvaginal mesh remains available for POP treatment. Long-term data of this cohort is currently being collected to further assess the safety of transvaginal mesh as a treatment for POP.

Keywords

urogynecological center

polypropylene mesh

pelvic organ prolapse

surgical outcomes

anatomical outcomes

symptom-related outcomes

patient satisfaction

transvaginal mesh

POP treatment

long-term data