E-Posters-Pattern of Bladder Sensation in Patients with Lower Urinary Tract Symptoms (LUTS) using a Water Load Protocol - Douglas G Tincello, BSc, MBChB, MD, FRCOG, FHEA

Pattern of Bladder Sensation in Patients with Lower Urinary Tract Symptoms (LUTS) using a Water Load Protocol - Douglas G Tincello, BSc, MBChB, MD, FRCOG, FHEA

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A study was conducted to evaluate the pattern of bladder sensation in patients with lower urinary tract symptoms (LUTS) using a water load protocol. The protocol required participants to consume 300ml of water every 15 minutes. Participants recorded their bladder sensations on a scale of 0-10 every 5 minutes. The void after reaching the strongest sensation was measured and participants continued for another filling cycle. Participants with a large difference in diuresis rate were excluded. Bladder sensation curves were plotted and compared between patients with different LUTS.<br /><br />A total of 69 patients completed the protocol, with a median age of 55.5 years and median BMI of 29.6 kg/m2. The study found a significant difference in bladder volumes among different LUTS groups. However, the area under the curve (AUC), which represents the shape of the sensation curves, was not significantly different between the groups. This suggests that bladder sensation develops in a similar way regardless of the type of LUTS.<br /><br />The findings of this study contradict the theory that overactive bladder (OAB) is primarily a sensory phenomenon from the urothelium, as bladder sensation was related to proportional volume and not specific to a particular LUTS group.<br /><br />Overall, the water load protocol proved to be a reliable method for evaluating bladder sensation in patients with LUTS. The study highlights the importance of understanding the patterns of bladder sensation in order to better diagnose and treat LUTS.

Keywords

bladder sensation

lower urinary tract symptoms

water load protocol

bladder volumes

diuresis rate

bladder sensation curves

LUTS groups

area under the curve

overactive bladder

urothelium