E-Posters-Relationship Between Nocturia and Detrusor Contractility

Relationship Between Nocturia and Detrusor Contractility - Hannah T. Ryles, MD

Pdf Summary

Nocturia, the need to wake up to urinate at night, has been associated with various urological symptoms and conditions in women. A study aimed to investigate the relationship between nocturia and detrusor contractility, which refers to the ability of the bladder muscle to contract and empty urine effectively.<br /><br />The study included female patients who underwent urodynamic testing at a single institution from 2015 to 2018. The patients were divided into two groups: those with nocturia (urinating two or more times per night) and those without nocturia (urinating zero to one time per night). <br /><br />The results showed that women with nocturia were less likely to report symptoms of pelvic organ prolapse and were diagnosed less often with pelvic organ prolapse and stress urinary incontinence. Nocturia was significantly associated with other urological symptoms and conditions such as urinary incontinence, frequency, urgency, overactive bladder, urge urinary incontinence, and mixed urinary incontinence. <br /><br />In terms of urodynamic parameters, women with nocturia had lower maximum and average flow rates, lower maximum cystometric capacity, and were less likely to void more than 100 mL on pressure flow studies. However, they were not significantly more likely to have detrusor underactivity or bladder voiding efficiencies below 90%. <br /><br />Overall, the study found that nocturia is significantly associated with abnormal detrusor contractility, including detrusor overactivity. However, a significant number of patients were unable to be categorized into specific urodynamic diagnoses due to missing data or not meeting diagnostic criteria.<br /><br />The study highlights the challenges in diagnosing abnormal detrusor contractility in women and the need for better measurements and definitions in this regard.

Keywords

nocturia

urological symptoms

detrusor contractility

urodynamic testing

pelvic organ prolapse

urinary incontinence

overactive bladder

urodynamic parameters

abnormal detrusor contractility

diagnostic criteria