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Urinary Tract Infections and Bacteriuria in Postme ...
Urinary Tract Infections and Bacteriuria in Postmenopausal Women with Pelvic Floor Dysfunction - Jittima Manonai, MD, MHM
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This study investigated the prevalence and risk factors of urinary tract infections (UTIs) and bacteriuria in postmenopausal women with pelvic floor dysfunction. The study included 420 women with pelvic floor dysfunction, and the mean age was 65.8 years. The most common pelvic floor symptoms were frequency/nocturia and stress urinary incontinence.<br /><br />The prevalence of symptomatic UTIs in these women was 7.4%, and 6.2% had asymptomatic bacteriuria. Escherichia coli was the most frequently isolated pathogen from urine cultures. Age, diabetes mellitus, pelvic floor symptoms, and prolapse stage were not found to be associated with the occurrence of UTIs.<br /><br />However, postmenopausal women with current UTIs were more likely to have a postvoid residual (PVR) volume greater than 100 mL. Antibiotics were prescribed to 69.2% of women with asymptomatic bacteriuria. Among women with symptomatic UTIs caused by E. coli, amoxicillin and clavulanic acid, trimethoprim/sulfamethoxazole, ciprofloxacin, and nitrofurantoin were the most commonly prescribed antibiotics.<br /><br />In conclusion, the prevalence of UTIs and bacteriuria in postmenopausal women with pelvic floor dysfunction was 7.4% and 6.2%, respectively. Higher postvoid residual volume was associated with a higher risk of UTIs. Escherichia coli was the most commonly isolated pathogen. Antibiotics were commonly prescribed for both symptomatic and asymptomatic bacteriuria.
Keywords
urinary tract infections
bacteriuria
postmenopausal women
pelvic floor dysfunction
prevalence
risk factors
symptoms
Escherichia coli
postvoid residual volume
antibiotics
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