E-Posters-Urodynamic Assessment of Bladder Storage Function after Querleu-Morrow Type C Radical Hysterectomy for Cervical Cancer：A Multicenter Cohort Study

Urodynamic Assessment of Bladder Storage Function after Querleu-Morrow Type C Radical Hysterectomy for Cervical Cancer：A Multicenter Cohort Study - Tingting Cao, MD

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This multicenter cohort study aimed to assess bladder storage function after Querleu-Morrow type C radical hysterectomy for cervical cancer. The study included 203 cervical cancer patients who underwent urodynamic studies (UDS) to evaluate bladder storage function. The incidence of lower urinary tract symptoms (LUTS) after the surgery ranged from 8% to 80%. The study identified risk factors for bladder storage dysfunction and protective factors for bladder storage symptoms.<br /><br />The results showed that 46.8% of patients were diagnosed with stress urinary incontinence (SUI), 23.2% had low compliance bladder (LBC), and 13.3% had detrusor overactivity (DO). Laparoscopy was found to be a protective factor for SUI, and nerve-sparing procedures also reduced the likelihood of experiencing SUI. LBC and DO showed a significant positive relationship. Risk factors for LBC and DO included a greater length of resected vagina and chemoradiotherapy, with radiotherapy having a higher influence than chemotherapy. Laparoscopic surgery was found to be unfavorable for DO. The follow-up time had no correlation with bladder storage function.<br /><br />Based on the findings, the authors recommended nerve-sparing procedures without dispensable radiotherapy or longer resected vagina to recover bladder storage function postoperatively. These results provide better treatment options for oncologists and contribute to understanding bladder storage function after radical hysterectomy for cervical cancer.<br /><br />The study was supported by the Beijing Municipal Science & Technology Commission and the authors declared no conflicts of interest.

Keywords

bladder storage function

Querleu-Morrow type C radical hysterectomy

cervical cancer

urodynamic studies

lower urinary tract symptoms

stress urinary incontinence

laparoscopy

nerve-sparing procedures

resected vagina

chemoradiotherapy