PFD Week 2018-General Session IV

Video Transcription

Video Summary

The video discusses several research studies related to pelvic floor disorders and their connection to pregnancy and childbirth. The first study focuses on the incidence of pelvic floor disorders in the first two decades after childbirth. It reveals that pelvic floor disorders, such as stress urinary incontinence (SUI), overactive bladder (OAB), anal incontinence (AI), and prolapse, are more common after vaginal delivery compared to cesarean delivery. The study also highlights the association between the size of the genital hiatus and the progression of prolapse. Factors such as delivery mode, race, parity, age at first delivery, and BMI are considered in determining the incidence of these disorders.<br /><br />The second study examines the role of levator ani muscle avulsion in the development of pelvic floor disorders. It reveals that levator avulsion is significantly associated with prolapse, but not with SUI, OAB, or AI. The study also demonstrates that levator avulsion affects the structure and function of the levator ani muscle.<br /><br />The third study explores the recovery of the vaginal wall after childbirth. It focuses on the role of fibulin 5, a glycoprotein that promotes elastogenesis and suppresses matrix metalloproteinase 9 (MMP9) in the vaginal tissue. The study reveals that pregnancy and delivery lead to a decrease in fibulin 5 expression, resulting in poor recovery of vaginal elasticity. The study also shows that the protease inhibitor actinonin improves the recovery of the vaginal wall by increasing fibulin 5 content, elastic fibers, collagen content, and biomechanical properties.<br /><br />Overall, these studies provide insights into the incidence, progression, and recovery of pelvic floor disorders, and highlight potential interventions to improve outcomes for women after childbirth.

Asset Subtitle

Joan L. Blomquist, MD, Lahari Nandikanti, Jennifer Joy Hamner, DO, & Victoria L. Handa, MD, MHS

Meta Tag

Category Pelvic Organ Prolapse

Category Education

Category Imaging

Keywords

pelvic floor disorders

pregnancy

childbirth

incidence

vaginal delivery